CBSE Class 12 Biotechnology Syllabus 2017-18

CBSE Class 12 Biotechnology Syllabus 2017-18

Download latest cbse Class 12 Biotechnology syllabus for the March 2018 exam. Class 12 Biotechnology Board exam will consist of 70 marks and 30 marks will be of practical. There is the separate syllabus for Biotechnology practical & it will be conducted in your schools but the external faculties will be there. That’s why you should also check it out.

Each year cbse keep on issuing revised syllabus. Although the topics and textbooks remain same, the topics and question pattern vary. Along with Biotechnology syllabus for class 12 cbse has also issued the chapter-wise breakup of questions along with weightage of each chapter. The package also enlists the learning objectives. That’s why it is recommended to download new Class 12 Biotechnology syllabus 2017-18  and be on safe side.

Here we have presented the CBSE syllabus for Biotechnology class 12 in the same format as released by CBSE, without any changes or editing from our side. Students are advised to download the Biotechnology class 12 syllabus by cbse for the March 2018 exam even if you have the previous year syllabus because there might be changes in the syllabus, question pattern and weightage of each chapter.

Click on the button below to download the syllabus in pdf format. Scroll down to view the detailed syllabus.

Biotechnology Class 12 Syllabus for March 2018 Exam 

More on Class 10 Syllabus


Detailed Syllabus Biotechnology Class 12 for March 2018 Board Exam

Unit V: Protein and Gene Manipulation

Chapter-1: Recombinant DNA Technology

Introduction; Tool of rDNA Technology; Marketing Recombinant DNA; Introduction of Recombinant DNA into Host Cells; Identification of Recombinants; DNA Library; DNA Probes; Hybridization Techniques; Polymerase Chain Reaction (PCR); DNA Secquencing; Site-directed Mutagenesis

Chapter-2: Protein Structure and Engineering

Introduction to the World of Proteins; 3-D Shape of Proteins; Structure-Function Relationship in Proteins Purification of Proteins; Characterization of Proteins; Protein based Products; Designing Proteins (protein engineering)

Chapter-3: Genomics and Bioinformatics

Introduction; Genome Sequencing Projects; Gene Prediction and Counting; Genome Similarity, SNPs and Comparative Genomics; Functional Genomics; Proteomics; History of Bioinformatics; Sequences and Nomenclature; Information Sources; Analysis using Bioinformatics Tools

Unit VI: Cell Culture and Genetic Manipulation

Chapter-1: Microbial Culture and Applications

Introduction, Microbial culture techniques, Measurement and kinetics of microbial growth, Scale up of microbial process, Isolation of microbial products, Strain isolation and improvement, Applications of microbial culture technology, Biosafety issues in microbial technology

Chapter-2: Plant Cell Culture and Applications

Introduction; Cell and Tissue Culture Techniques; Applications of Cell and Tissue Culture; Gene Transfer Methods in Plants; Transgenic Plants with Beneficial Traits; Biosafety in Plant Genetic Engineering

Chapter-3: Animal Cell Culture and Applications

Introduction, Animal cell culture techniques, Characterisation of cell lines, Methods of gene delivery into cells, Scale-up of animal culture process, Applications of animal cell culture, Stem cell technology, Tissue engineering


  1. Use of special equipment in biotechnology experiments.
  2. Isolation of bacterial plasmid DNA
  3. Detection of DNA by gel electrophoreses
  4. Isoloation of Genomic DNA (CTAB method)
  5. Estimation of DNA
  6. Bacterial transformation using any plasmid
  7. Restriction digestion of plasmid DNA & its analysis by gel electrophoreses
  8. Isolation of bacterial grom curd & staining of bacteria
  9. Cell viability assay
  10. Data retrieval and data base search using internet site NCBI and download a DNA and protein sequence from internet, analyse it and comment on it
  11. Reading of a DNA sequencing gel to arrive at the sequence
  12. Project work


Prescribed Books:

1. A Text Book of Biotechnology – Class XII : Published by CBSE, New Delhi
2. A Laboratory Manual of Biotechnology – Class XII : Published by CBSE, New Delhi


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